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Image Search Results
Journal: Antioxidants
Article Title: Arctium lappa Root Extract Prevents Lead-Induced Liver Injury by Attenuating Oxidative Stress and Inflammation, and Activating Akt/GSK-3β Signaling
doi: 10.3390/antiox8120582
Figure Lengend Snippet: ALRE activates Akt/GSK-3β signaling in liver of Pb(II)-induced rats. ( A ) Representative blots of pAkt, Akt, pGSK-3β, GSK-3β, and β-actin. ( B , C ) ALRE and Vit. C increased the levels of pAkt ( B ) and pGSK-3β ( C ). Data are expressed as mean ± SEM, ( n = 6). *** p < 0.001.
Article Snippet: After blocking, the membranes were probed with antibodies against pAkt Ser473, Akt, pGSK-3β Ser9,
Techniques:
Journal: Antioxidants
Article Title: Arctium lappa Root Extract Prevents Lead-Induced Liver Injury by Attenuating Oxidative Stress and Inflammation, and Activating Akt/GSK-3β Signaling
doi: 10.3390/antiox8120582
Figure Lengend Snippet: A schematic diagram illustrating the protective mechanism of A. lappa root extract (ALRE) on Pb(II)-induced liver injury. Pb(II) provokes reactive oxygen species (ROS) generation which activates NF-κB, and stimulates GSK-3β, resulting in inflammation and cell death via apoptosis. ALRE suppresses ROS production, boosts antioxidant defenses and activates Akt which phosphorylates/deactivates GSK-3β.
Article Snippet: After blocking, the membranes were probed with antibodies against pAkt Ser473, Akt, pGSK-3β Ser9,
Techniques: